FRANKIE
.308 Win
With the two calibers you just mentioned, (338 lapua/RUM)By Classic definitions, the .375 H&H was considered the minimum for African "Big Five" but now they utilize power factor formulas...I have a .376 Steyr whose case is not physically as large, but operates under higher pressures, giving it close to the same velocity. (think .308 v. 30'06)
I think the key lies in how big a hole and how deep it goes...I wonder how a high quality bullet from either a .338 Lapua/RUM would perform versus the same weight in a .375?
I would say pretty damn good.
I wanna say superior